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Implications of ultrasonically diagnosed polycystic ovaries. II. Studies of dynamic and pulsatile hormonal patterns
- Source :
- Human Reproduction. 7:458-461
- Publication Year :
- 1992
- Publisher :
- Oxford University Press (OUP), 1992.
-
Abstract
- Studies of 6-h hormone pulse patterns distinguished patients with polycystic ovarian disease (PCOD) from those with hyperprolactinaemia or hypothyroidism associated with ultrasonically diagnosed polycystic ovaries (PCO). No specific derangement in the gonadotrophin pulse pattern was responsible for these changes, as shown in patients with and without PCO in the latter two groups. These changes may reflect an abnormal ovarian response to normal or abnormal gonadotrophic drive. Out of 26 patients with PCO and elevated dehydroepiandrosterone sulphate (DHEA-S) levels, only three patients (11.5%) proved to have adrenal 21-hydroxylase deficiency. Ultrasonic visualization of polycystic ovaries must be supplemented with an endocrine biochemical assessment. Moreover, mild elevation of DHEA-S, without a concurrently high 17 alpha-hydroxyprogesterone level was not diagnostic of adrenal hyperplasia.
- Subjects :
- Adult
Periodicity
endocrine system
medicine.medical_specialty
Hydrocortisone
medicine.drug_class
Pulsatile flow
Biology
Hyperthyroidism
Sex Hormone-Binding Globulin
Internal medicine
Adrenal Glands
medicine
Humans
Endocrine system
Testosterone
Ultrasonography
Estradiol
Dehydroepiandrosterone Sulfate
Rehabilitation
Hyperprolactinaemia
Obstetrics and Gynecology
Dehydroepiandrosterone
Luteinizing Hormone
Hyperplasia
medicine.disease
Polycystic ovary
Hormones
Prolactin
Polycystic ovarian disease
Hyperprolactinemia
Endocrinology
Reproductive Medicine
Female
Follicle Stimulating Hormone
Gonadotropin
hormones, hormone substitutes, and hormone antagonists
Polycystic Ovary Syndrome
Hormone
Subjects
Details
- ISSN :
- 14602350 and 02681161
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Human Reproduction
- Accession number :
- edsair.doi.dedup.....478087c6f95e4f7c3a0ea3587238a44c