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Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments
- Source :
- Diabetic Foot & Ankle, Diabetic Foot & Ankle, Vol 6, Iss 0, Pp 1-10 (2015), Diabetic Foot & Ankle; Vol 6 (2015)
- Publication Year :
- 2015
- Publisher :
- Co-Action Publishing, 2015.
-
Abstract
- Negative-pressure wound therapy (NPWT) plays an important role in the treatment of complex wounds. Its effect on limb salvage in the management of the diabetic foot is well described in the literature. However, a successful outcome in this subgroup of diabetic patients requires a multidisciplinary approach with careful patient selection, appropriate surgical debridement, targeted antibiotic therapy, and optimization of healing markers. Evolving NPWT technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve results if used with correct indications. This review article summarizes current knowledge about the role of NPWT in the management of the diabetic foot and its mode of action, clinical applications, and recent developments.Keywords: vacuum therapy; subatmospheric pressure dressing; topical negative-pressure therapy; diabetic ulcers; wound bed preparation; amputation(Published: 1 July 2015)Citation: Diabetic Foot & Ankle 2015, 6: 27618 - http://dx.doi.org/10.3402/dfa.v6.27618
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Limb salvage
lcsh:Surgery
wound bed preparation
Review Article
topical negative-pressure therapy
vacuum therapy
Wound bed preparation
Negative-pressure wound therapy
Antibiotic therapy
amputation
Internal Medicine
lcsh:Pathology
Medicine
diabetic ulcers
Podiatry
subatmospheric pressure dressing
business.industry
Surgical debridement
lcsh:RD1-811
medicine.disease
Diabetic foot
Review article
Surgery
Amputation
business
lcsh:RB1-214
Subjects
Details
- Language :
- English
- ISSN :
- 2000625X
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Diabetic Foot & Ankle
- Accession number :
- edsair.doi.dedup.....47cfde93218f59b80bd33579686a94b3