Higher Frequency of Germinal Matrix-Intraventricular Hemorrhage in Moderate and Late Preterm and Early Term Neonates with Intrauterine Growth Restriction Compared to Healthy Ones

Germinal matrix-intraventricular brain hemorrhage is mostly found in preterm neonates, but may also occur in term neonates. The aim of this study was to analyze the prevalence and severity of this type of hemorrhage in moderate and late preterm and early term neonates with intrauterine growth restriction. In the prospective analysis, 100 newborns were examined, i.e. 70 with intrauterine growth restriction and 30 as a control group. Study subjects were neonates from 32 0/7 to 38 6/7 gestational weeks. Body weight, body length, head circumference and ponderal index at birth were analyzed. Hemorrhage was assessed by cranial ultrasound using Papile classification. Out of 70 neonates with intrauterine growth restriction, germinal matrix-intraventricular hemorrhage was not found in 36 (51.43%) neonates, 31 (44.29%) had hemorrhage grade 1, and three (4.29%) had hemorrhage grade 2, which was statistically significant (p
Periventrikulsko-intraventrikulsko krvarenje u mozgu uglavnom se nalazi u nedonoščadi, ali se također može pojaviti kod djece rođene u terminu. Cilj ovog istraživanja bio je analizirati učestalost i ozbiljnost ovog tipa krvarenja kod umjerene i kasne nedonoščadi i rane terminske novorođenčadi s intrauterinim zastojem u rastu. U prospektivnoj analizi ispitano je 100 novorođenčadi: 70 s intrauterinim zastojem u rastu i 30 kao kontrolna skupina. Ispitanici su bili novorođenčad od 32 0/7 do 38 6/7 tjedana gestacije. Analizirana je tjelesna težina, duljina tijela, opseg glave i ponderalni indeks pri rođenju. Krvarenje je određeno klasifikacijom Papile, uz pomoć ultrazvučne pretrage mozga. U 36 (51,43%) od 70 novorođenčadi s intrauterinim zastojem u rastu nije pronađeno periventrikulsko-intraventrikulsko krvarenje, 31 (44,29%) je imalo krvarenje 1. stupnja, dok ih je 3 (4,29%) imalo krvarenje 2. stupnja, što je bilo statistički značajno (p