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Outcomes in patients with moderate and asymptomatic severe aortic stenosis followed up in heart valve clinics

Authors :
Pasquale Paolisso
Monika Beles
Marta Belmonte
Emanuele Gallinoro
Cristina De Colle
Niya Mileva
Dario Tino Bertolone
Celine Deschepper
Jerrold Spapen
Sofie Brouwers
Ivan Degrieck
Filip Casselman
Bernard Stockman
Frank Van Praet
Martin Penicka
Carlos Collet
Eric Wyffels
Marc Vanderheyden
Emanuele Barbato
Jozef Bartunek
Guy Van Camp
Internal Medicine
Pharmaceutical and Pharmacological Sciences
Experimental Pharmacology
Clinical sciences
Source :
Heart. 109:634-642
Publication Year :
2022
Publisher :
BMJ, 2022.

Abstract

BackgroundHeart valve clinics (HVC) have been introduced to manage patients with valvular heart disease within a multidisciplinary team.ObjectiveTo determine the outcome benefit of HVC approach compared with standard of care (SOC) for patients with moderate and asymptomatic severe aortic stenosis (mAS and asAS).MethodsSingle-centre, observational registry of patients with mAS and asAS with at least one cardiac ambulatory consultation at our Cardiovascular Centre. Based on the outpatient strategy, patients were divided into HVC group, if receiving at least one visit at HVC, and SOC group, if followed by routine cardiac consultations.Results2129 patients with mAS and asAS were divided into those followed in HVC (n=251) versus SOC group (n=1878). The mean age was 76.5±12.4 years; 919 (43.2%) had asAS. During a follow-up of 4.8±1.8 years, 822 patients (38.6%) died, 307 (14.4%) were hospitalised for heart failure and 596 (28%) underwent aortic valve replacement (AVR). After propensity score matching, the number of consultations per year, exercise stress tests, brain natriuretic peptide (BNP) determinations and CTs were higher in the HVC cohort (pConclusionsIn patients with mAS and asAS, the HVC approach was associated with more efficient management and outcome benefit compared with SOC.

Details

ISSN :
1468201X and 13556037
Volume :
109
Database :
OpenAIRE
Journal :
Heart
Accession number :
edsair.doi.dedup.....4872cdb8728bb9b0b570b0262925fef0