The efficacy of taurolidine containing lock solutions for the prevention of central-venous-catheter-related bloodstream infections: a systematic review and meta-analysis

Authors :: Bernadette Jeremiasse
C.H. van den Bosch
Florine N. J. Frakking
Yvette G.T. Loeffen
Marc H. W. A. Wijnen
Marta Fiocco
M.D. van de Wetering
C.P. van de Ven
A.F.W. van der Steeg
T. van der Bruggen
Source :: Journal of Hospital Infection, 123, 143-155. W B SAUNDERS CO LTD
Publication Year :: 2022
Publisher :: W B SAUNDERS CO LTD, 2022.
Abstract: The incidence of central venous catheter (CVC)-related bloodstream infections is high in patients requiring a long-term CVC. Therefore, infection prevention is of the utmost importance. The aim of this study was to provide an updated overview of randomized controlled trials (RCTs) comparing the efficacy of taurolidine containing lock solutions (TL) to other lock solutions for the prevention of CVC-related bloodstream infections in all patient populations. On 15th February 2021, PubMed, Embase and The Cochrane Library were searched for RCTs comparing the efficacy of TLs for the prevention of CVC-related bloodstream infections with other lock solutions. Exclusion criteria were non-RCTs, studies describing

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