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EAACI position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis
- Source :
- Allergy, Allergy, 2019, 74 (8), pp.1429-1444. ⟨10.1111/all.13764⟩, Allergy, Wiley, 2019, 74 (8), pp.1429-1444. ⟨10.1111/all.13764⟩, Venter, C, Meyer, R W, Nwaru, B I, Roduit, C, Untersmayr, E, Adel-Patient, K, Agache, I, Agostoni, C, Akdis, C A, Bischoff, S, du Toit, G, Feeney, M, Frei, R, Garn, H, Greenhawt, M, Hoffmann-Sommergruber, K, Lunjani, N, Maslin, K, Mills, C, Muraro, A, Pali, I, Poulson, L, Reese, I, Renz, H, Roberts, G C, Smolinska, S, Sokolowska, M, Vlieg-Boerstra, B & O'Mahony, L 2019, ' EAACI position paper : Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis ', Allergy . https://doi.org/10.1111/all.13764
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- International audience; The prevalence of allergic diseases such as allergic rhinitis, asthma, food allergy, and atopic dermatitis has increased dramatically during the last decades, which is associated with altered environmental exposures and lifestyle practices. The purpose of this review was to highlight the potential role for dietary fatty acids, in the prevention and management of these disorders. In addition to their nutritive value, fatty acids have important immunoregulatory effects. Fatty acid-associated biological mechanisms, human epidemiology, and intervention studies are summarized in this review. The influence of genetics and the microbiome on fatty acid metabolism is also discussed. Despite critical gaps in our current knowledge, it is increasingly apparent that dietary intake of fatty acids may influence the development of inflammatory and tolerogenic immune responses. However, the lack of standardized formats (ie, food versus supplement) and standardized doses, and frequently a lack of prestudy serum fatty acid level assessments in clinical studies significantly limit our ability to compare allergy outcomes across studies and to provide clear recommendations at this time. Future studies must address these limitations and individualized medical approaches should consider the inclusion of specific dietary factors for the prevention and management of asthma, food allergy, and atopic dermatitis.
- Subjects :
- 0301 basic medicine
Allergy
Lydia Becker Institute
[SDV]Life Sciences [q-bio]
allergic
chemistry.chemical_compound
0302 clinical medicine
Epidemiology
Immunology and Allergy
Rhinitis
2. Zero hunger
dietary fatty acids
Fatty Acids
Age Factors
Atopic dermatitis
3. Good health
Food Hypersensitivity
altered environmenta
Signal Transduction
Adult
medicine.medical_specialty
Immunology
Dermatitis, Atopic
Immunomodulation
03 medical and health sciences
Immune system
Food allergy
ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation
Manchester Institute of Biotechnology
medicine
Animals
Humans
Microbiome
Nutrition
Asthma
Fatty acid metabolism
business.industry
Infant, Newborn
Infant
ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology
Lipid Metabolism
medicine.disease
Dietary Fats
Disease Models, Animal
030104 developmental biology
030228 respiratory system
chemistry
business
Subjects
Details
- ISSN :
- 13989995 and 01054538
- Database :
- OpenAIRE
- Journal :
- Allergy
- Accession number :
- edsair.doi.dedup.....48b30f1508b28f1d72b175e7e64dee0f