Back to Search
Start Over
Factors predictive for delayed enhancement in cardiac resonance imaging in patients undergoing catheter ablation of premature ventricular complexes
- Source :
- Heart Rhythm O2, Vol 2, Iss 1, Pp 64-72 (2021), Heart Rhythm O2
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Background: Patients undergoing ablation of premature ventricular complexes (PVCs) can have cardiac scar. Risk factors for the presence of scar are not well defined. Objectives: To determine the prevalence of scarring detected by delayed enhancement cardiac magnetic resonance imaging (DE-CMR) in patients undergoing ablation of PVCs, to create a risk score predictive of scar, and to explore correlations between the scoring system and long-term outcomes. Methods: DE-CMR imaging was performed in consecutive patients with frequent PVCs referred for ablation. The full sample was used to develop a prediction model for cardiac scar based on demographic and clinical characteristics, and internal validation of the prediction model was done using bootstrap samples. Results: The study consisted of 333 patients (52% male, aged 53.2 ± 14.5 years, preablation ejection fraction 50.9% ± 12.2%, PVC burden 20.7 ± 13.14), of whom 112 (34%) had DE-CMR scarring. Multiple logistic regression analysis showed age (odds ratio [OR] 1.02 [1.01–1.04]/year, P = .019) and preablation ejection fraction (OR 0.92 [0.89–0.94]/%, P < .001) to be predictive of scar. A weighted risk score incorporating age and ejection fraction was used to stratify patients into low-, medium-, and high-risk groups. Scar prevalence was around 86% in the high-risk group and 12% in the low-risk group; high-risk patients had worse survival free of arrhythmia. Conclusions: Cardiac scar was present in one-third of patients referred for PVC ablation. A weighted risk score based simply on patient age and preprocedural ejection fraction can help discriminate between patients at high and low risk for the presence of cardiac scar and worse arrhythmia outcomes.
- Subjects :
- Imaging/Mapping
medicine.medical_specialty
medicine.medical_treatment
Cardiac scar
Catheter ablation
Delayed enhancement
030204 cardiovascular system & hematology
Premature ventricular complexes
Clinical
03 medical and health sciences
0302 clinical medicine
Cardiac magnetic resonance imaging
Internal medicine
medicine
Diseases of the circulatory (Cardiovascular) system
030212 general & internal medicine
Risk stratification
Delayed enhancement cardiac magnetic resonance imaging
Framingham Risk Score
Ejection fraction
medicine.diagnostic_test
business.industry
Odds ratio
Ablation
RC666-701
Cardiology
business
Subjects
Details
- ISSN :
- 26665018
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Heart Rhythm O2
- Accession number :
- edsair.doi.dedup.....48c03f0b0453a96fdfc9b25d35fa455d