A study of some 'acute phase reactants' in rheumatic diseases

Representative “acute phase reactants” and a “clinical index” of synovial in flammation were determined in patients with various rheumatic diseases. The serum hexose-protein (PR) ratio, serum protein-bound hexose and seromucoid determinations were consistently found a more reliable indication of the extent of systemic inflammation than the other tests studied. Systemic inflammation, measured by “acute phase reactants,” paralleled the clinically determined synovial reaction only in patients with rheumatoid arthritis. Representative “reactantes de phase acute” e un “indice clinic” de inflammation synovial esseva determinate in patientes con vane morbos rheumatic. Le proportion de hexosa a proteina in le sero, le hexosa ligate a proteina seral, e le seromucoides se provava uniformemente plus fidel como indices del extension de inflammation systemic que le altere parametros studiate. Le inflammation systemic, mesurate per „reactantes de phase acute,” esseva parallel a1 clinicamente determinate reaction synovial solmente in patientes con arthritis rheumatoide.