Back to Search
Start Over
Supine and Standing Plasma Catecholamines in Essential Hypertensive Patients with Different Renin Levels
- Source :
- Clinical and Experimental Hypertension. Part A: Theory and Practice. 6:1119-1130
- Publication Year :
- 1984
- Publisher :
- Informa UK Limited, 1984.
-
Abstract
- In this study we measured plasma renin activity (PRA), plasma norepinephrine (NE) and epinephrine (E), heart rate (HR) and blood pressure (BP) in 89 supine (sup) essential hypertensive patients (pts), WHO I-II, after 3-5 days of fixed normal sodium and potassium intake; the same measurements were repeated after 30' of active standing (stand) in 44/89 pts. In the whole population NE was directly related to PRA, both in sup and in stand position (p less than 0.01). NE was above the upper limits of normotensive controls in 2/34 (6%) pts with low PRA, in 6/40 (17%) pts with normal PRA and in 6/15 (40%) pts with high PRA. In respect to normal PRA pts, HR was significantly lower in low PRA pts and higher in high PRA pts, both in sup and in stand position (p less than 0.05). Sup and stand NE and E were similar in low and normal PRA pts, while they were significantly higher in high PRA pts (p less than 0.05). These results suggest an increased adrenergic tone at least in some high PRA pts, and blunted responsiveness of renal and cardiac beta adrenergic receptors to adrenergic stimuli in low PRA pts.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
animal structures
Supine position
Epinephrine
Posture
Population
Adrenergic
Blood Pressure
macromolecular substances
urologic and male genital diseases
Essential hypertension
Plasma renin activity
Norepinephrine
Catecholamines
Heart Rate
Internal medicine
Renin
Heart rate
Blood plasma
Internal Medicine
medicine
Humans
education
Aged
education.field_of_study
business.industry
Middle Aged
medicine.disease
female genital diseases and pregnancy complications
Blood pressure
Endocrinology
Hypertension
Female
business
circulatory and respiratory physiology
Subjects
Details
- ISSN :
- 07300077
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Clinical and Experimental Hypertension. Part A: Theory and Practice
- Accession number :
- edsair.doi.dedup.....48d2fbab7b853450ea5eb8da0c495a10