Back to Search
Start Over
Radical radiation therapy of breast cancer
- Source :
- International journal of radiation oncology, biology, physics. 6(1)
- Publication Year :
- 1980
-
Abstract
- The 5 year results of radical radiation therapy in operable, infiltrating breast cancer (T1, T2, T3; NO, N1a, N1b) in 177 patients are presented. The treatment protocol included a pre-radiotherapy tumorectomy for T1 and certain T2 tumors (those less than 3cm diameter). Patients with larger tumors were treated by radiotherapy alone. The treatment technique incorporated both conventional fractionated radiotherapy (60 Co and electrons) and endocurietherapy (192 Ir). At 5 years, the uncorrected, disease-free survival rates were 84 % for T1, 79% for T2 and 56% for T3: loco-regional persistent or recurrent disease was seen in 4.5 % of patients with Tl disease, 7.5 % of those with T2, and 23 % of T3 patients; 16 mastectomies had been performed. Of the patients with T1 and T2 disease, 95 % had retained their breast and the esthetic result was judged to be good in 75 %. We recommend this technique of radical radiotherapy in early breast cancer because of this high rate of tumor control, associated with a low rate of normal tissue damage and survival figures comparable to those achieved by radical surgery.
- Subjects :
- Cancer Research
medicine.medical_specialty
medicine.medical_treatment
Brachytherapy
Normal tissue
Breast Neoplasms
Electrons
Iridium
Radiotherapy, High-Energy
Breast cancer
medicine
Recurrent disease
Humans
Radiology, Nuclear Medicine and imaging
Radical surgery
Cobalt Radioisotopes
High rate
Radioisotopes
Radiation
business.industry
Radical radiotherapy
Radiotherapy Dosage
Radiotherapy alone
medicine.disease
Surgery
Radiation therapy
Oncology
Female
Radiology
Radioisotope Teletherapy
business
Subjects
Details
- ISSN :
- 03603016
- Volume :
- 6
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- International journal of radiation oncology, biology, physics
- Accession number :
- edsair.doi.dedup.....4903e6da9a92eddb7d2a3edde20a00fe