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Correction: Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus)

Authors :
Klena Sarges Marruaz da Silva
Gyselly de Cássia Bastos de Matos
Rosane do Socorro Pompeu de Loiola
Délia Cristina Figueira Aguiar
Washington Luiz Assunção Pereira
Tereza Cristina de Oliveira Corvelo
Source :
PLoS ONE, Vol 16, Iss 10, p e0259504 (2021), PLoS ONE, Vol 15, Iss 11, p e0241487 (2020), PLoS ONE, PLoS ONE, Vol 16, Iss 10 (2021)
Publication Year :
2021
Publisher :
Public Library of Science (PLoS), 2021.

Abstract

ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact with the external environment and may serve as ligands for pathogens in tissues or block their connection. Description of the distribution of these molecules in non-human primate tissues is restricted to a few tissues and species. This paper describes the expression of human A, B and H type antigens in different organs from four species of New World Primates, obtained from the Centro Nacional de Primatas, as well as comparing that expression with what has been described for humans. In this study, although the tissue description of the antigens is similar to the genetic model for humans, some differences in expression between some organs from those species and those of humans were found. The differences occurred mainly in endodermal organs that have secretory functions and are probably under the control of the human-type FUT-2 enzyme. In the mesodermal-origin organs there was a reduction or absence of A and B antigen marking, particularly in the H precursor substance, indicating that those organs are under the control of the human-type FUT-1 enzyme. These findings have demonstrated that there is similar ABH antigen reactivity in tissue distribution between the species, although there are some species-specific cases.

Details

Language :
English
ISSN :
19326203
Volume :
16
Issue :
10
Database :
OpenAIRE
Journal :
PLoS ONE
Accession number :
edsair.doi.dedup.....4949023fe2255b4898e2b526e02a44ed