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Correction: Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus)
- Source :
- PLoS ONE, Vol 16, Iss 10, p e0259504 (2021), PLoS ONE, Vol 15, Iss 11, p e0241487 (2020), PLoS ONE, PLoS ONE, Vol 16, Iss 10 (2021)
- Publication Year :
- 2021
- Publisher :
- Public Library of Science (PLoS), 2021.
-
Abstract
- ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact with the external environment and may serve as ligands for pathogens in tissues or block their connection. Description of the distribution of these molecules in non-human primate tissues is restricted to a few tissues and species. This paper describes the expression of human A, B and H type antigens in different organs from four species of New World Primates, obtained from the Centro Nacional de Primatas, as well as comparing that expression with what has been described for humans. In this study, although the tissue description of the antigens is similar to the genetic model for humans, some differences in expression between some organs from those species and those of humans were found. The differences occurred mainly in endodermal organs that have secretory functions and are probably under the control of the human-type FUT-2 enzyme. In the mesodermal-origin organs there was a reduction or absence of A and B antigen marking, particularly in the H precursor substance, indicating that those organs are under the control of the human-type FUT-1 enzyme. These findings have demonstrated that there is similar ABH antigen reactivity in tissue distribution between the species, although there are some species-specific cases.
- Subjects :
- Physiology
030204 cardiovascular system & hematology
Monkeys
Biochemistry
Epithelium
Salivary Glands
0302 clinical medicine
Immune Physiology
Medicine and Health Sciences
Primate
Tissue Distribution
Saimiri
chemistry.chemical_classification
Mammals
Immune System Proteins
Multidisciplinary
biology
Eukaryota
Callithrix
Body Fluids
Platyrrhini
Phenotypes
Blood
Organ Specificity
Sapajus apella
Vertebrates
Aotidae
Medicine
Anatomy
Aotus infulatus
Research Article
Primates
Science
030231 tropical medicine
Immunology
ABO Blood-Group System
03 medical and health sciences
Exocrine Glands
Antigen
Species Specificity
biology.animal
Genetic model
Genetics
Animals
Pharmacokinetics
Antigens
Pharmacology
New World monkeys
Biology and life sciences
Organisms
Saimiri sciureus
Proteins
Correction
biology.organism_classification
Molecular biology
Enzyme
Biological Tissue
chemistry
Tissue expression
Amniotes
Zoology
Digestive System
Blood Groups
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 16
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....4949023fe2255b4898e2b526e02a44ed