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Prevention of progression of Parkinson's disease with antioxidative therapy

Authors :
Jay H. Thakar
Mohamed N. Hassan
J.David Crimes
Source :
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 12:165-172
Publication Year :
1988
Publisher :
Elsevier BV, 1988.

Abstract

Grimes, J.D., Hassan, M.N., Thakar, J.H.: Prevention of Progression of Parkinson's Disease with Antioxidative Therapy. Prog. Neuro. Psychopharmacol. & Biol. Psychiat. 1988, 12 :165–172 1. 1. Oxidative mechanisms in dopaminergic neurons may contribute to cell death and the progression of Parkinson's Disease. 2. 2. The free radical auto-toxicity concept has scientific evidence to support it. 3. 3. Clinical trials are underway to assess the protective effect of augmenting the free radical scavenging system with vitamin E and inhibiting catecholamine oxidation with deprenyl.

Details

ISSN :
02785846
Volume :
12
Database :
OpenAIRE
Journal :
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Accession number :
edsair.doi.dedup.....497697931a656c43d9c80acc5c6ceec2
Full Text :
https://doi.org/10.1016/0278-5846(88)90034-6