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Assessment of the QoL in Italian menopausal women: comparison between HRT users and non-users
- Source :
- Maturitas. 42:267-280
- Publication Year :
- 2002
- Publisher :
- Elsevier BV, 2002.
-
Abstract
- Objectives: The aim of this cross-sectional study was to describe QoL in a large sample of women attending menopause centres and compare untreated postmenopausal women and matched HRT users by employing the Women's Health Questionnaire (WHQ) and two generic instruments, the SF-36 and the EQ-5D. Methods: Overall, 2906 women were recruited by 64 menopause centres throughout Italy, of whom 2160 filled in the questionnaire (1093 on HRT and 1067 not on HRT; response rate: 74%). Results: HRT users tended to be younger, healthier and with shorter menopause duration as opposed to non users, while no major socio-economic differences were present. At multivariate analysis, the presence of chronic diseases, low socio-economic status and living in Southern Italy represented the most important predictors of poor QoL. Furthermore, HRT users showed a lower probability of reporting problems in usual activities and pain/discomfort (EQ-5D), role limitations due to emotional problems (SF-36) and anxiety/fears (WHQ). HRT users also showed highly significant better outcomes in those areas that are more directly attributable to hormonal changes of mid age, namely vasomotor symptoms and sexual problems. Conclusions: Although QoL is mainly influenced by socio-economic and cultural factors, HRT has the potential for improving not only symptoms, but also more general aspects of physical and psychological well-being of symptomatic postmenopausal women.
- Subjects :
- Gerontology
medicine.medical_specialty
Multivariate analysis
Psychometrics
HRT
Health Status
General Biochemistry, Genetics and Molecular Biology
Quality of life
Surveys and Questionnaires
Epidemiology
Humans
Medicine
Gynecology
Response rate (survey)
business.industry
Public health
Estrogen Replacement Therapy
Female
Italy
Menopause
Middle Aged
Multivariate Analysis
Quality of Life
Questionnaires
Socioeconomic Factors
Obstetrics and Gynecology
medicine.disease
Anxiety
sense organs
medicine.symptom
business
Subjects
Details
- ISSN :
- 03785122
- Volume :
- 42
- Database :
- OpenAIRE
- Journal :
- Maturitas
- Accession number :
- edsair.doi.dedup.....49a519bb1dac1ec7caa21d42ae8a661c