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THREE MONOCLONAL ANTIBODIES SPECIFIC FOR HUMAN CLASS II ANTIGENS DETECT RT1B-LINKED POLYMORPHISMS IN RAT B CELLS
- Source :
- European Journal of Immunogenetics. 11:255-258
- Publication Year :
- 1984
- Publisher :
- Wiley, 1984.
-
Abstract
- SUMMARY Three monoclonal antibodies HU-11, HU-32, and HU-33, which recognize two distinct polymorphic determinants of human class II antigens, were found to cross-react with rat B cells carrying an RT1B region-associated specificity Ba-2.6. This is the first report demonstrating that xenoimmune antibodies raised against polymorphic determinants of human class II antigens are able to detect polymorphic determinants of class II antigens in a third party species.
- Subjects :
- Anticorps monoclonal
Genetic Linkage
medicine.drug_class
Immunology
Cross Reactions
Monoclonal antibody
Species Specificity
Antigen
HLA Antigens
Histocompatibility Antigens
Genetics
medicine
Animals
Humans
HLA-D Antigens
B-Lymphocytes
Polymorphism, Genetic
biology
Third party
Antibodies, Monoclonal
Rats, Inbred Strains
Molecular biology
Rats
biology.protein
Antibody
Class II Antigens
Subjects
Details
- ISSN :
- 13652370 and 09607420
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- European Journal of Immunogenetics
- Accession number :
- edsair.doi.dedup.....4a0484ec98a183ae51584aa90a89676c