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Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension
- Source :
- Pulmonary Circulation, Vol 9 (2019), Pulmonary Circulation
- Publication Year :
- 2019
- Publisher :
- SAGE Publishing, 2019.
-
Abstract
- Pulmonary arterial compliance (PAC), invasively assessed by the ratio of stroke volume to pulmonary arterial (PA) pulse pressure, is a sensitive marker of right ventricular (RV)-PA coupling that differs across the spectrum of pulmonary hypertension (PH) and is predictive of outcomes. We assessed whether the echocardiographically derived ratio of RV outflow tract velocity time integral to PA systolic pressure (RVOT-VTI/PASP) (a) correlates with invasive PAC, (b) discriminates heart failure with preserved ejection-associated PH (HFpEF-PH) from pulmonary arterial hypertension (PAH), and (c) is associated with functional capacity. We performed a retrospective cohort study of patients with PAH (n = 70) and HFpEF-PH (n = 86), which was further dichotomized by diastolic pressure gradient (DPG) into isolated post-capillary PH (DPG
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system
non-invasive
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine.artery
pulmonary hypertension
medicine
Ventricular outflow tract
cardiovascular diseases
lcsh:RC705-779
business.industry
Non invasive
Stroke volume
lcsh:Diseases of the respiratory system
medicine.disease
Pulmonary hypertension
Pulse pressure
Compliance (physiology)
Blood pressure
030228 respiratory system
lcsh:RC666-701
Pulmonary artery
Cardiology
pulmonary arterial compliance
Cpc-PH
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 20458940
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Pulmonary Circulation
- Accession number :
- edsair.doi.dedup.....4a3573a60c49c4f7755a42badefd97d0