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The Value of Preprocedural MR Imaging in Genicular Artery Embolization for Patients with Osteoarthritic Knee Pain
- Source :
- Journal of Vascular and Interventional Radiology. 31:2043-2050
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- PURPOSE To determine the value of preprocedural MR imaging in genicular artery embolization (GAE) for patients with osteoarthritic knee pain. MATERIALS AND METHODS This single-center study retrospectively analyzed 28 knees in 18 patients who underwent GAE for intractable knee pain < 1 month after MR imaging. The pain experienced in each knee was evaluated on a 100-mm visual analog scale (VAS) at baseline and 1- and 3-month after GAE. "GAE responders" were defined as knees that exhibited greater than 30% reduction of VAS pain scores from baseline at both follow-up visits. Musculoskeletal radiologists evaluated MR images of the affected knee compartment regarding cartilage defects, osteophytes, subchondral cysts, bone marrow lesions (BMLs), meniscal injury, and joint effusion. The performances of Kellgren-Lawrence (KL) grading and MR findings in predicting GAE responders was estimated based on receiver operating characteristic curves. RESULTS The mean VAS pain score was 84.3 mm. BML (area under the curve [AUC], 0.860; P < .001), meniscal injury (AUC, 0.811; P = .003), and KL grading (AUC, 0.898; P < .001) were significantly associated with GAE outcome. To predict GAE responders, KL grade ≤ 2 yielded a sensitivity of 87.5% and a specificity of 60.9%, BML grade ≤ 1 yielded a sensitivity of 75.0% and a specificity of 69.6%, and meniscal injury grade ≤ 2 yielded a sensitivity of 83.3% and a specificity of 72.7%. CONCLUSIONS Large BMLs and severe meniscal injuries on MR imaging, as well as high KL grades, indicated poor responses to GAE.
- Subjects :
- Male
Genicular artery
Knee Joint
Visual analogue scale
Clinical Decision-Making
Osteoarthritis
Severity of Illness Index
Predictive Value of Tests
medicine
Humans
Radiology, Nuclear Medicine and imaging
Aged
Pain Measurement
Retrospective Studies
Aged, 80 and over
Receiver operating characteristic
business.industry
Patient Selection
Area under the curve
Arteries
Middle Aged
Osteoarthritis, Knee
Joint effusion
medicine.disease
Arthralgia
Embolization, Therapeutic
Treatment Outcome
Knee pain
medicine.anatomical_structure
Predictive value of tests
Female
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Nuclear medicine
Magnetic Resonance Angiography
Subjects
Details
- ISSN :
- 10510443
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Journal of Vascular and Interventional Radiology
- Accession number :
- edsair.doi.dedup.....4a39c3f2f17a700a8a83736172558f81