The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on Rac1 level and migration of medulloblastoma in vitro

Authors :: Leonie F. Schoen
Rogerio B. Craveiro
Torsten Pietsch
Thomas Moritz
Anja Troeger
Silvia Jordans
Dagmar Dilloo
Source :: Journal of cellular and molecular medicine : JCMM 26(23), 5832-5845 (2022). doi:10.1111/jcmm.17604
Publication Year :: 2022
Publisher :: RWTH Aachen University, 2022.
Abstract: Journal of cellular and molecular medicine : JCMM 26(23), 5832-5845 (2022). doi:10.1111/jcmm.17604<br />Published by Wiley-Blackwell, Hoboken, NJ

Subjects :: rac1 GTP-Binding Protein
Phosphatidylinositol 3-Kinases
Cell Movement
Cell Line, Tumor
Molecular Medicine
Humans
Cell Biology
Sorafenib
Cerebellar Neoplasms
Medulloblastoma
Phosphoinositide-3 Kinase Inhibitors

Language :: English
Database :: OpenAIRE
Journal :: Journal of cellular and molecular medicine : JCMM 26(23), 5832-5845 (2022). doi:10.1111/jcmm.17604
Accession number :: edsair.doi.dedup.....4b0bf97707bc26be175f055bd5dc9846
Full Text :: https://doi.org/10.18154/rwth-conv-250424

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