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Red blood cell distribution width and outcome in trauma patients
- Source :
- Journal of osteopathic medicine
- Publication Year :
- 2021
-
Abstract
- Context Red blood cell distribution width (RDW) has been used to predict mortality during infection and inflammatory diseases. It also been purported to be predictive of mortality following traumatic injury. Objective To identify the role of RDW in predicting mortality in trauma patients. We also sought to identify the role of RDW in predicting the development of sepsis in trauma patients. Methods A retrospective observational study was performed of the medical records for all adult trauma patients admitted to Loyola University Medical Center from 2007 to 2014. Patients admitted for fewer than four days were excluded. Admission, peak, and change from admission to peak (Δ) RDW were recorded to determine the relationship with in-hospital mortality. Patient age, development of sepsis during the hospitalization, admission to the intensive care unit (ICU), and discharge disposition were also examined. Results A total of 9,845 patients were admitted to the trauma service between 2007 and 2014, and a total of 2,512 (25.5%) patients fit the inclusion criteria and had both admission and peak values available. One-hundred twenty (4.6%) died while in the hospital. RDW values for all patients were (mean [standard deviation, SD]): admission 14.09 (1.88), peak 15.09 (2.34), and Δ RDW 1.00 (1.44). Admission, peak, and Δ RDW were not significant predictors of mortality (all p>0.50; hazard ratio [HR], 1.01–1.03). However, trauma patients who eventually developed sepsis had significantly higher RDW values (admission RDW: 14.27 (2.02) sepsis vs. 13.98 (1.73) no sepsis, p Conclusion Admission, peak, and Δ RDW were not associated with in-hospital mortality in adult trauma patients with a length of stay (LOS) ≥four days. However, the development of sepsis in trauma patients is closely linked to increased RDW values and in-hospital mortality.
- Subjects :
- Complementary and Manual Therapy
Adult
Erythrocyte Indices
Male
medicine.medical_specialty
Erythrocytes
Adolescent
Context (language use)
030204 cardiovascular system & hematology
Article
law.invention
Sepsis
sepsis
03 medical and health sciences
Young Adult
0302 clinical medicine
Patient age
law
Internal medicine
medicine
Humans
Hospital Mortality
Aged
Retrospective Studies
business.industry
Medical record
Hazard ratio
030208 emergency & critical care medicine
Red blood cell distribution width
Retrospective cohort study
Middle Aged
medicine.disease
Intensive care unit
mortality
Intensive Care Units
trauma
Complementary and alternative medicine
Wounds and Injuries
Female
red blood cell distribution width
business
red blood cells
Subjects
Details
- Language :
- English
- ISSN :
- 27023648
- Volume :
- 121
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of osteopathic medicine
- Accession number :
- edsair.doi.dedup.....4b13991dfece627421ff37cf5fb91358