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Supplement Figure 3 from Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition

Authors :
Christopher C. Benz
Scott D. Pegan
Bryan J. Cowen
Byron Hann
Martin Borch Jensen
Sophia Mahoney
Sana Khateeb
Beatrice C. Becker
Christina Yau
Gary K. Scott
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplement Figure 3. Confocal images of control and N-PPG treated ZR-75-1 cell cultures show absence of mitochondrial membrane recruitment of PINK/PARKIN complex (A), despite positive induction of mitochondrial GRP-75 import (B), within 24 h of N-PPG treatment.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....4b33f1896c6d7e4bfd6bd84510e053ff
Full Text :
https://doi.org/10.1158/1535-7163.22506033