Back to Search
Start Over
National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers
- Source :
- University of Helsinki
- Publication Year :
- 2016
-
Abstract
- Background: Updated National Academy of Clinical Biochemistry (NACB) Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been developed.Methods: Published reports relevant to use of tumor markers for 5 cancer sites—testicular, prostate, colorectal, breast, and ovarian—were critically reviewed.Results: For testicular cancer, α-fetoprotein, human chorionic gonadotropin, and lactate dehydrogenase are recommended for diagnosis/case finding, staging, prognosis determination, recurrence detection, and therapy monitoring. α-Fetoprotein is also recommended for differential diagnosis of nonseminomatous and seminomatous germ cell tumors. Prostate-specific antigen (PSA) is not recommended for prostate cancer screening, but may be used for detecting disease recurrence and monitoring therapy. Free PSA measurement data are useful for distinguishing malignant from benign prostatic disease when total PSA is Conclusions: Implementation of these recommendations should encourage optimal use of tumor markers.
- Subjects :
- Oncology
Male
medicine.medical_specialty
Colorectal cancer
medicine.medical_treatment
Clinical Biochemistry
Breast Neoplasms
03 medical and health sciences
0302 clinical medicine
Breast cancer
Carcinoembryonic antigen
Testicular Neoplasms
Reference Values
Internal medicine
medicine
Biomarkers, Tumor
Humans
Testicular cancer
030304 developmental biology
Gynecology
Ovarian Neoplasms
0303 health sciences
biology
business.industry
Clinical Laboratory Techniques
Biochemistry (medical)
Cancer
Prostatic Neoplasms
medicine.disease
3. Good health
Prostate cancer screening
030220 oncology & carcinogenesis
biology.protein
Female
Hormone therapy
business
Ovarian cancer
Colorectal Neoplasms
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- University of Helsinki
- Accession number :
- edsair.doi.dedup.....4b737ea1564c10835360f51d51f29049