Back to Search
Start Over
Increased Pulmonary Arterial Compliance after Balloon Pulmonary Angioplasty Predicts Exercise Tolerance Improvement in Inoperable CTEPH Patients with Lower Pulmonary Arterial Pressure
- Source :
- Heartlung : the journal of critical care. 52
- Publication Year :
- 2021
-
Abstract
- Background Balloon pulmonary angioplasty (BPA) improved pulmonary arterial compliance (CPA) and exercise tolerance in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Objectives To investigate whether CPA is a useful index to indicate exercise tolerance improvement by BPA in CTEPH patients. Methods The correlation between changes in CPA and improvements in 6-minute walk distance (6MWD) by BPA was retrospectively analyzed in 70 patients (Analysis 1), and it was sequentially analyzed in 46 symptomatic patients who achieved mean pulmonary arterial pressure (mPAP) Results We enrolled 70 patients (female/male:57/13, mean age:59 years) who underwent a total of 352 BPA sessions which significantly increased CPA (1.5±0.8 vs. 3.0±1.0 mL/mmHg) and decreased pulmonary vascular resistance (PVR) (8.0 ± 3.9 vs. 3.6 ± 1.7 wood units). The correlation coefficient between improvement in 6MWD and changes in PVR and CPA were r=0.21 (p=0.09) and r=0.14 (p=0.26) (Analysis 1). In Analysis 2, those were r=0.32 (p=0.06) and r=0.38 (p=0.02), respectively. Conclusions CPA can be a useful index to indicate the improvement in exercise tolerance by BPA in symptomatic patients with lower mPAP.
- Subjects :
- Pulmonary and Respiratory Medicine
Male
medicine.medical_specialty
medicine.medical_treatment
Hypertension, Pulmonary
Pulmonary arterial pressure
Pulmonary Artery
Critical Care and Intensive Care Medicine
Balloon
Angioplasty
Internal medicine
medicine
Humans
In patient
Arterial Pressure
Retrospective Studies
Exercise Tolerance
business.industry
Wood units
Middle Aged
Compliance (physiology)
medicine.anatomical_structure
Treatment Outcome
Chronic Disease
Vascular resistance
Cardiology
Chronic thromboembolic pulmonary hypertension
Female
Cardiology and Cardiovascular Medicine
business
Pulmonary Embolism
Angioplasty, Balloon
Subjects
Details
- ISSN :
- 15273288
- Volume :
- 52
- Database :
- OpenAIRE
- Journal :
- Heartlung : the journal of critical care
- Accession number :
- edsair.doi.dedup.....4b8c83c37b3d357b46de9027698e4feb