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EOSINOPHILS AND IL-5 RECEPTOR IN COVID-19 POSTMORTEM LUNG TISSUE

Authors :
David Chain
Christopher Mccrae
Weiguang Zhao
Ron Chen
Adrian Freeman
Jennifer Cann
Rohit K. Katial
Allen Mcalexander
Karma Dacosta
Andrew Jones
Hitesh Sanganee
Source :
Chest
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

TOPIC: Chest Infections TYPE: Original Investigations PURPOSE: Severe COVID-19 infections have been associated with alterations in blood eosinophil counts and elevated blood interleukin (IL)-5 levels [1,2]. The aim of this study was to explore whether eosinophils and IL-5 receptors are observed in post-mortem lung tissue from patients with COVID-19 pneumonia. METHODS: Hematoxylin & eosin (HE584(7821):463–9. 2. Rodriguez L, Pekkarinen PT, Lakshmikanth T, et al. Systems-level immunomonitoring from acute to recovery phase of severe COVID-19. Cell Rep Med. 2020;1(5):100078. DISCLOSURES: Employee relationship with AstraZeneca Please note: 7.5 years Added 04/30/2021 by Jennifer Cann, source=Web Response, value=stock grants No relevant relationships by David Chain, source=Web Response Employee relationship with AstraZeneca Please note: 15/06/2020 Added 04/30/2021 by Ron Chen, source=Web Response, value=Salary No relevant relationships by Karma Dacosta, source=Web Response No relevant relationships by Adrian Freeman, source=Web Response Employee relationship with AstraZeneca Please note: 1996 to date Added 04/29/2021 by Andrew Jones, source=Web Response, value=Salary Stock Owner relationship with AstraZeneca Please note: 1996 to date Added 04/29/2021 by Andrew Jones, source=Web Response, value=Stock Owner Employee relationship with astrazeneca Please note: current Added 04/30/2021 by Rohit Katial, source=Web Response, value=Salary Employee relationship with AstraZeneca Please note: July 2019-present Added 04/29/2021 by Allen McAlexander, source=Web Response, value=Salary Employee relationship with AstraZeneca Please note: Jul 1999 to present Added 04/29/2021 by Christopher McCrae, source=Web Response, value=Salary Employee relationship with AstraZeneca Please note: Jul 1999 to present Added 04/29/2021 by Christopher McCrae, source=Web Response, value=Ownership interest No relevant relationships by Hitesh Sanganee, source=Web Response No relevant relationships by WEIGUANG ZHAO, source=Web Response

Details

ISSN :
00123692
Volume :
160
Database :
OpenAIRE
Journal :
Chest
Accession number :
edsair.doi.dedup.....4bf064083f4299ec7f0b76d0472d69ba
Full Text :
https://doi.org/10.1016/j.chest.2021.07.548