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Aberrant Fatty Acid-Binding Protein-7 Gene Expression in Cutaneous Malignant Melanoma
- Source :
- Journal of Investigative Dermatology. 130(1):221-229
- Publication Year :
- 2010
- Publisher :
- Elsevier BV, 2010.
-
Abstract
- Fatty acid-binding protein-7 (FABP7) has been shown to be expressed in cutaneous melanoma; however, its role in tumor progression is unclear. Expression of FABP7 was assessed during melanoma progression through assessment of various clinicopathology stages of primary tumor progression and metastasis. FABP7 mRNA was highly expressed in 60 of 87 (69%) primary melanomas, compared with significant (P
- Subjects :
- Pathology
medicine.medical_specialty
Skin Neoplasms
Loss of Heterozygosity
Kaplan-Meier Estimate
Dermatology
Biology
Biochemistry
Disease-Free Survival
Article
Fatty acid-binding protein
Metastasis
03 medical and health sciences
0302 clinical medicine
Cell Line, Tumor
medicine
Humans
RNA, Messenger
Melanoma
neoplasms
Molecular Biology
030304 developmental biology
0303 health sciences
Reverse Transcriptase Polymerase Chain Reaction
Tumor Suppressor Proteins
Cancer
Cell Biology
FABP7
Neoplastic Cells, Circulating
medicine.disease
Primary tumor
3. Good health
Gene Expression Regulation, Neoplastic
Tumor progression
030220 oncology & carcinogenesis
Multivariate Analysis
Cutaneous melanoma
Disease Progression
Cancer research
Chromosomes, Human, Pair 6
Carrier Proteins
Fatty Acid-Binding Protein 7
Microsatellite Repeats
Subjects
Details
- ISSN :
- 0022202X
- Volume :
- 130
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Investigative Dermatology
- Accession number :
- edsair.doi.dedup.....4c4732a1531685d0a569e6c2e4359e87
- Full Text :
- https://doi.org/10.1038/jid.2009.195