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Toward discovery science of human brain function
- Source :
- Proceedings of the National Academy of Sciences, 107(10), 4734-4739, Proceedings of the National Academy of Sciences USA, 107, 10, pp. 4734-9, Proceedings of the National Academy of Sciences USA, 107, 4734-9, Proceedings of the National Academy of Sciences of the United States of America
- Publication Year :
- 2010
-
Abstract
- Although it is being successfully implemented for exploration of the genome, discovery science has eluded the functional neuroimaging community. The core challenge remains the development of common paradigms for interrogating the myriad functional systems in the brain without the constraints of a priori hypotheses. Resting-state functional MRI (R-fMRI) constitutes a candidate approach capable of addressing this challenge. Imaging the brain during rest reveals large-amplitude spontaneous low-frequency (www.nitrc.org/projects/fcon_1000/ .
- Subjects :
- Adult
Male
Adolescent
Computer science
Membrane transport and intracellular motility [NCMLS 5]
Computational biology
Neuroinformatics [DCN 3]
Bioinformatics
Brain mapping
Young Adult
Sex Factors
Neuroimaging
Functional neuroimaging
Neural Pathways
medicine
Humans
Aged
Discovery science
Analysis of Variance
Brain Mapping
Multidisciplinary
medicine.diagnostic_test
Resting state fMRI
Age Factors
Brain
Human brain
Middle Aged
Biological Sciences
Magnetic Resonance Imaging
medicine.anatomical_structure
database neuroimaging open access reproducibility resting state resting-state networks base-line sexual-dimorphism connectivity mri architecture cortex fmri fluctuations activation
Connectome
Female
Functional magnetic resonance imaging
Algorithms
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Database :
- OpenAIRE
- Journal :
- Proceedings of the National Academy of Sciences, 107(10), 4734-4739, Proceedings of the National Academy of Sciences USA, 107, 10, pp. 4734-9, Proceedings of the National Academy of Sciences USA, 107, 4734-9, Proceedings of the National Academy of Sciences of the United States of America
- Accession number :
- edsair.doi.dedup.....4d0686a4b8fac730bf9cc3baad5cfc53