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Risk factors and distribution of oncogenic strains of human papilloma virus in women presenting for cervical cancer screening in Port Harcourt, Nigeria
- Source :
- Pan African Medical Journal; Vol 23, No 1 (2016), The Pan African Medical Journal, The Pan African Medical Journal, Vol 23, Iss 85 (2016)
- Publication Year :
- 2016
- Publisher :
- African Field Epidemiology Network, 2016.
-
Abstract
- Introduction: Human papilloma virus(HPV) accounts for most cases of cervical cancer with high risk HPV(hrHPV) genotypes largely responsible. The objective is to ascertain the distribution of oncogenic strains of human papilloma virus genotypes and predisposing risk factors in women presenting for cervical cancer screening in Nigeria. Methods: A cross-sectional study of 80 women who presented for cervical cancer screening. The biodata of the participants, the presence of risk factors to HPV were recorded and hrHPV were identified using PCR technique. The information obtained was processed using the SPSS version 20 software. Results were presented in tables, test of significance and association done using student's t-test and Odds ratio, with P value < 0.05 as significant. Results: The age range of patients was 19-62 years with prevalence of hrHPV of 10%. HrHPV are more in patients with more than one life time sexual partner (OR 1.26,95%CI 0.13-29.99), multiple sexual partners (OR 1.55, 95% CI 0.28-8.70), early coitarche (OR 1.57, 95% CI 0.14-15.00) and previous STI (OR 150, 95%CI 9.53-1979. 62). Four hrHPV genotypes: 16, 18, 31 and 35 were detected. Conclusion: HPV genotype 18 was predominant in Port Harcourt, Nigeria. High risk sexual behaviours are associated with acquisition of hrHPV.Pan African Medical Journal 2016; 23
- Subjects :
- Sexual partner
Cross-sectional study
Uterine Cervical Neoplasms
Cervical cancer screening
Polymerase Chain Reaction
0302 clinical medicine
Risk Factors
Genotype
Mass Screening
Papillomaviridae
Young adult
Early Detection of Cancer
Cervical cancer
lcsh:R5-920
biology
Obstetrics
lcsh:Public aspects of medicine
General Medicine
Middle Aged
Sexual Partners
030220 oncology & carcinogenesis
Female
lcsh:Medicine (General)
Adult
HPV
medicine.medical_specialty
Sexual Behavior
prevalence
030231 tropical medicine
Nigeria
Port Harcourt
Young Adult
03 medical and health sciences
medicine
Humans
In patient
Mass screening
Gynecology
Human papilloma virus
business.industry
Research
Papillomavirus Infections
lcsh:RA1-1270
General Chemistry
Odds ratio
biology.organism_classification
medicine.disease
Cross-Sectional Studies
Port harcourt
business
Subjects
Details
- Language :
- English
- ISSN :
- 19378688
- Database :
- OpenAIRE
- Journal :
- Pan African Medical Journal
- Accession number :
- edsair.doi.dedup.....4d2d9476b3a93223d24e0bc9df450dc7