Use of an Alcohol-Free Mouth Rinse Containing Cetylpyridnium Chloride may Lower Risk for the Incidence of Preterm Birth

Article Title and Bibliographic Information Use of alcohol-free antimicrobial mouth rinse is associated with decreased incidence of preterm birth in a high risk population. Jeffcoat M, Parry S, Gerlach RW, Doyle MJ. Am J Obstet Gynecol 2011:205:382.e1-6. Epub 2011 Jul 20. Reviewer David P. Cappelli, DMD, MPH, PhD Purpose/Question To determine if treatment of periodontal disease during pregnancy with an alcohol-free antimicrobial mouth rinse containing 0.07% cetylpyridinium chloride (CPC) affects the incidence of preterm birth (PTB) in a high-risk population Source of Funding Commonwealth of Pennsylvania, Harrisburg, Pennsylvania, and The Procter and Gamble Company, Mason, Ohio (educational grant) Type of Study/Design Controlled clinical trial Level of Evidence Level 2: Limited-quality, patient-oriented evidence Strength of Recommendation Grade Not applicable