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Rapid detection of urokinase plasminogen activator using flexible paper-based graphene-gold platform
- Source :
- Biointerphases
- Publication Year :
- 2020
- Publisher :
- American Vacuum Society, 2020.
-
Abstract
- Many studies have shown that urokinase plasminogen activator (uPA) is causally involved in promoting cancer invasion and metastasis. Thus, monitoring uPA levels could be very useful in cancer diagnosis, identification of initial metastasis, and guiding cancer treatment. Here, the authors developed a novel and scalable uPA sensor based on a graphene-gold nanoparticle platform that uses fluorescence of quantum dots to rapidly (
- Subjects :
- Paper
General Physics and Astronomy
Metal Nanoparticles
Biosensing Techniques
Rapid detection
General Biochemistry, Genetics and Molecular Biology
Antibodies
Metastasis
Biomaterials
Limit of Detection
Neoplasms
Sense (molecular biology)
medicine
Humans
General Materials Science
Density Functional Theory
Immunoassay
Chemistry
Urokinase Plasminogen Activator
Cancer
General Chemistry
Paper based
Articles
medicine.disease
Urokinase-Type Plasminogen Activator
Recombinant Proteins
Cancer treatment
Cancer research
Graphite
Gold
Fetal bovine serum
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Biointerphases
- Accession number :
- edsair.doi.dedup.....4d659266148d36fb994f25611da653e4