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Intensification of yeast production with microbubbles
- Source :
- Food and Bioproducts Processing. 100:424-431
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Yeast requires and consumes a high amount of oxygen rapidly during growth. Maintaining yeast cultures under sufficient aeration, however, is a significant challenge in yeast propagation. Due to their high surface area, microbubbles are more efficient in mass transfer than coarse bubbles. The performance of an airlift loop bioreactor equipped with a fluidic oscillator generated microbubbles in yeast propagation is presented here. The approach is compared with a conventional bubble generation method that produces coarse bubbles. Dosing with microbubbles transferred more oxygen to the cultures, achieving non-zero dissolved O2 levels and consequently, eliminating the starvation state of yeast in contrast to coarse bubble sparging. The average cell growth yield obtained under microbubble sparging reached 0.31 mg/h (±0.02) while 0.22 mg/h (±0.01) was recorded for cells grown with coarse bubbles during the log phase. The percent difference in average growth yield after 6 hours was 18%. Additionally, the use of microbubbles in yeast harvest from growth medium proved effective, yielding >99% cell recovery. The result of this study is crucial for the biofuel industry but also, the food, nutraceutical and pharmaceutical industry for which end product purity is premium.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Chemistry
General Chemical Engineering
Airlift
Nanotechnology
Bacterial growth
7. Clean energy
01 natural sciences
Biochemistry
Yeast
03 medical and health sciences
030104 developmental biology
Chemical engineering
010608 biotechnology
Microbubbles
Bioreactor
Fermentation
Aeration
Sparging
Food Science
Biotechnology
Subjects
Details
- ISSN :
- 09603085
- Volume :
- 100
- Database :
- OpenAIRE
- Journal :
- Food and Bioproducts Processing
- Accession number :
- edsair.doi.dedup.....4d6996076a490a6c04ab463ce8bbeddb