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Early Diagnosis of Colorectal Cancer in Rats With DMH Induced Carcinogenesis by Means of Urine Autofluorescence Analysis
- Source :
- Photochemistry and Photobiology. 90:682-685
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- Cancer is one of the most highlighted topics of current research. Early detection of this disease allows more effective therapy, hence higher chance of cure. Application of fluorescence spectral techniques into oncological diagnostic is one of the potential alternatives. Chemically induced carcinogenesis in rats is widely used model for exploration of various aspects of colorectal cancer. This study shows value of discriminate analysis of urine fluorescent fingerprint between healthy control group of rats and those with dimethylhydrazine induced early lesions of colorectal cancer. Using fluorescence spectroscopy, significant difference (P < 0.05) between both of group was achieved.
- Subjects :
- Dimethylhydrazines
Colorectal cancer
business.industry
Significant difference
Cancer
General Medicine
Urine
Disease
medicine.disease_cause
medicine.disease
Biochemistry
Rats
Rats, Sprague-Dawley
Autofluorescence
Early Diagnosis
Carcinogens
medicine
Dimethylhydrazine
Cancer research
Animals
Physical and Theoretical Chemistry
Colorectal Neoplasms
Carcinogenesis
business
Subjects
Details
- ISSN :
- 00318655
- Volume :
- 90
- Database :
- OpenAIRE
- Journal :
- Photochemistry and Photobiology
- Accession number :
- edsair.doi.dedup.....4d70fc0042445753679325e6d21bb521