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Withdrawal of Combination Immunotherapy in Paediatric Inflammatory Bowel Disease—An International Survey of Practice
- Source :
- Journal of pediatric gastroenterology and nutrition, 73(1), 54-60. Lippincott Williams and Wilkins, Meredith, J, Henderson, P, Wilson, D C, Van Limbergen, J, Wine, E & Russell, R 2021, ' Withdrawal of combination immunotherapy in paediatric inflammatory bowel disease – an international survey of practice ', Journal of pediatric gastroenterology and nutrition . https://doi.org/10.1097/MPG.0000000000003098
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- OBJECTIVES: To assess current practices around the use of combination immunosuppression in paediatric inflammatory bowel disease (PIBD) with a focus on the subsequent withdrawal process. METHODS: A web-based, 43-question survey. RESULTS: Surveys were completed by 70 paediatric gastroenterologists (PGs) from 27 nations across Europe, North America, Oceania and Asia from 62 centres covering approximately 15,000 PIBD patients (median of 200 patients [interquartile range (IQR) 130-300] per centre). Routine use of co-immunosuppression was significantly higher with infliximab (IFX) versus adalimumab (ADL) ([61/70, 87.1%] compared with [23/70, 32.9%]; P
- Subjects :
- medicine.medical_specialty
Asia
Combination therapy
Azathioprine
Withdrawal time
Inflammatory bowel disease
03 medical and health sciences
0302 clinical medicine
Interquartile range
030225 pediatrics
Internal medicine
Adalimumab
Humans
Immunologic Factors
Medicine
Child
business.industry
Gastroenterology
Inflammatory Bowel Diseases
medicine.disease
Ulcerative colitis
Infliximab
Europe
North America
Pediatrics, Perinatology and Child Health
Drug Therapy, Combination
030211 gastroenterology & hepatology
Immunotherapy
business
Immunosuppressive Agents
medicine.drug
Subjects
Details
- ISSN :
- 15364801 and 02772116
- Volume :
- 73
- Database :
- OpenAIRE
- Journal :
- Journal of Pediatric Gastroenterology & Nutrition
- Accession number :
- edsair.doi.dedup.....4dbd6fdaa9802a07787a45ca5cd8b9f6