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APOE signaling is a common pathway in microglia in neurodegeneration

Authors :
Krasemann, Susanne
Madore, Charlotte
O´Loughlin, Elaine
Cialic, Ron
Fanek, Zain
El Fatimy, Rachid
Greco, David
Smith, Scott
Tweet, Georg
Mazaheri, Fargol
Conde-Sanroman, Patricia
Garcias, Mar
Calcagno, Narghes
Glatzel, Markus
Worthmann, Anna
Heeren, Joerg
Lemere, Cynthia
Vanderburg, Charles
Heppner, Frank
Budnik, Bogdan
Ikezu, Tsuneya
Lassmann, Hans
Weiner, Howard
Ochando, Jordi
Haass, Christian
Butovsky, Oleg
Source :
Joint-Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) and the Scandinavian Neuropathological Society (SNS); 20160922-20160924; Hamburg; DOC16dgnnND5 /20160914/
Publication Year :
2016
Publisher :
German Medical Science GMS Publishing House; Düsseldorf, 2016.

Abstract

Microglia are the immune cells of the brain. They play a dual role by promoting homeostatic functions in the healthy brain, but acquiring dysregulated properties in neurodegenerative and neuroinflammatory diseases. How this switch in the microglia phenotype is executed on the molecular level is still[for full text, please go to the a.m. URL]<br />Joint-Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) and the Scandinavian Neuropathological Society (SNS)

Details

Language :
English
Database :
OpenAIRE
Journal :
Joint-Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) and the Scandinavian Neuropathological Society (SNS); 20160922-20160924; Hamburg; DOC16dgnnND5 /20160914/
Accession number :
edsair.doi.dedup.....4dee0cc9e8fcdd36bcecad0b84dc8cfe