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Neuronal regulation of longevity by staying cool
- Source :
- Genesdevelopment. 32(3-4)
- Publication Year :
- 2018
-
Abstract
- Aging is fundamental to life and reflects functional declines in different tissues at the organismal level. As a systematic process, aging can be influenced by the interplay between genetic and environmental factors, and the nervous system plays a crucial role in this regulation. Environmental inputs can be sensed by the nervous system, which consequently triggers signaling outputs toward peripheral tissues to regulate gene expression systematically. Thus, understanding the underlying molecular mechanisms behind environmentally triggered neuron–periphery cross-talk is crucial for the promotion of an organism's health and longevity.
- Subjects :
- 0301 basic medicine
Nervous system
Neurons
media_common.quotation_subject
Longevity
Brain
Biology
biology.organism_classification
03 medical and health sciences
030104 developmental biology
medicine.anatomical_structure
Gene expression
Genetics
medicine
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Neuroscience
Organism
Developmental Biology
media_common
Research Paper
Subjects
Details
- ISSN :
- 15495477
- Volume :
- 32
- Issue :
- 3-4
- Database :
- OpenAIRE
- Journal :
- Genesdevelopment
- Accession number :
- edsair.doi.dedup.....4dfcdda529a731ff9f42530c05641e72