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Drug-Eluting Stent vs Percutaneous Transluminal Angioplasty for Treatment of Femoropopliteal In-Stent Restenosis: Results From a Retrospective 1-Year Multicenter Study
- Source :
- Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 23(4)
- Publication Year :
- 2016
-
Abstract
- Purpose: To compare drug-eluting stent (DES) implantation with percutaneous transluminal angioplasty (PTA) in the treatment of femoropopliteal in-stent restenosis (ISR). Methods: A comparison was performed of data from 112 ZEPHYR registry patients (mean age 74±9 years; 60 men) with 119 femoropopliteal ISR lesions treated with a drug-eluting stent (Zilver PTX) with historical data from 116 patients (mean age 72±8 years; 83 men) with 133 lesions treated with PTA. The patients were stratified for analysis by lesions with (101/252, 40%) and without (n=151) in-stent occlusion. The primary outcome measure was the 1-year incidence of recurrent restenosis; the secondary outcome was major adverse limb events (MALE). Multivariate logistic regression analysis was performed to look for any independent association of DES implantation with 1-year recurrent restenosis in the respective subgroups; results are presented as the odds ratio (OR) and 95% confidence interval (CI). Results: In the subgroup without in-stent occlusion, there was no significant difference between DES and PTA in the 1-year incidence of recurrent restenosis (40.5% vs 45.7%, p=0.583, respectively) or MALE (27.8% vs 20.7%, p=0.322, respectively). However, in the subgroup with in-stent occlusion, DES implantation was associated with significantly lower incidences of recurrent restenosis (44.1% vs 90.3% for PTA, p
- Subjects :
- Male
medicine.medical_specialty
Percutaneous
Time Factors
medicine.medical_treatment
030204 cardiovascular system & hematology
Prosthesis Design
03 medical and health sciences
Peripheral Arterial Disease
0302 clinical medicine
Restenosis
Japan
Recurrence
Risk Factors
medicine.artery
medicine
Odds Ratio
Humans
Radiology, Nuclear Medicine and imaging
Popliteal Artery
030212 general & internal medicine
Registries
Vascular Patency
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Stent
Retrospective cohort study
Drug-Eluting Stents
Odds ratio
Middle Aged
medicine.disease
Confidence interval
Popliteal artery
Surgery
Femoral Artery
Logistic Models
Treatment Outcome
Drug-eluting stent
Multivariate Analysis
Retreatment
Female
Radiology
Cardiology and Cardiovascular Medicine
business
Angioplasty, Balloon
Subjects
Details
- ISSN :
- 15451550
- Volume :
- 23
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
- Accession number :
- edsair.doi.dedup.....4e1f11d77fdf091499567753bb918f04