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Opsoclonus-induced occipital deactivation with a region-specific distribution
- Source :
- University of Groningen, Vision Research, 41(9), 1209-1214. PERGAMON-ELSEVIER SCIENCE LTD
- Publisher :
- Elsevier Science Ltd.
-
Abstract
- The cerebral distribution of 2-[18F]fluoro 2-deoxy-D-glucose (FDG) uptake in a patient with opsoclonus was measured by positron emission tomography (PET) and subsequently compared with the distribution in ten normal subjects. Statistical parametric mapping (SPM) revealed a decreased occipital FDG uptake in the patient, particularly at the posterior bank of the parieto-occipital sulcus (putative visual area PO/V6), in the region ventrally bordering V5, and anterolaterally in the calcarine sulcus. Such a specific pattern of occipital deactivation may indicate that opsoclonus suppresses the processing of visual motion along the magnocellular pathway. This is in agreement with normal saccadic suppression which has been proposed to contribute to the perception of a stable visual space. (C) 2001 Elsevier Science Ltd. Ail rights reserved.
- Subjects :
- MACAQUE MONKEY
MOTION
genetic structures
FLOW
Motion Perception
ORGANIZATION
Statistical parametric mapping
Extrastriate cortex
Ocular Motility Disorders
Fluorodeoxyglucose F18
AREAS
medicine
Humans
FIELD
SUPPRESSION
Brain Mapping
medicine.diagnostic_test
Chemistry
Opsoclonus
Anatomy
Sulcus
medicine.disease
Saccadic masking
Sensory Systems
Calcarine sulcus
Ophthalmology
medicine.anatomical_structure
PET
Positron emission tomography
Case-Control Studies
HUMAN VISUAL-CORTEX
Occipital Lobe
Radiopharmaceuticals
EYE-MOVEMENTS
Occipital lobe
Neuroscience
POSITRON-EMISSION TOMOGRAPHY
Tomography, Emission-Computed
Oculomotor
Subjects
Details
- Language :
- English
- ISSN :
- 00426989
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Vision Research
- Accession number :
- edsair.doi.dedup.....4e553afa19617a8679789d37dcce8248
- Full Text :
- https://doi.org/10.1016/S0042-6989(01)00006-2