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Adverse events associated with immune checkpoint inhibitor treatment for cancer
- Source :
- Canadian Medical Association Journal. 191:E40-E46
- Publication Year :
- 2019
- Publisher :
- CMA Joule Inc., 2019.
-
Abstract
- Key points Inhibitors against cytotoxic T-lymphocyte–associated protein 4 and programmed cell death 1 immune checkpoints are novel agents that modulate immune pathways and enhance anti-tumour immunity. Their use has set new standards in the treatment of many cancer types. Some patients with
- Subjects :
- 0301 basic medicine
animal diseases
Immune checkpoint inhibitors
Programmed Cell Death 1 Receptor
chemical and pharmacologic phenomena
Review
03 medical and health sciences
Antineoplastic Agents, Immunological
0302 clinical medicine
Immune system
Immunity
Neoplasms
Programmed cell death 1
Humans
Medicine
Cytotoxic T cell
CTLA-4 Antigen
Adverse effect
biology
business.industry
Cancer
Cell Cycle Checkpoints
General Medicine
biochemical phenomena, metabolism, and nutrition
medicine.disease
030104 developmental biology
Immune System Diseases
Novel agents
030220 oncology & carcinogenesis
Cancer research
biology.protein
bacteria
business
Subjects
Details
- ISSN :
- 14882329 and 08203946
- Volume :
- 191
- Database :
- OpenAIRE
- Journal :
- Canadian Medical Association Journal
- Accession number :
- edsair.doi.dedup.....4e9c0a024366c929fa8420fb97917e35
- Full Text :
- https://doi.org/10.1503/cmaj.180870