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Combined Multimorbidity and Polypharmacy Patterns in the Elderly: A Cross-Sectional Study in Primary Health Care
- Source :
- International Journal of Environmental Research and Public Health, Vol 18, Iss 9216, p 9216 (2021), International Journal of Environmental Research and Public Health, Volume 18, Issue 17, Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona, Dipòsit Digital de la UB, Universidad de Barcelona
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Altres ajuts: Pla Estratègic de Recerca i Innovació en Salut (PERIS), SLT002/16/00058 Background: The acquisition of multiple chronic diseases, known as multimorbidity, is common in the elderly population, and it is often treated with the simultaneous consumption of several prescription drugs, known as polypharmacy. These two concepts are inherently related and cause an undue burden on the individual. The aim of this study was to identify combined multimorbidity and polypharmacy patterns for the elderly population in Catalonia. Methods: A cross-sectional study using electronic health records from 2012 was conducted. A mapping process was performed linking chronic disease categories to the drug categories indicated for their treatment. A soft clustering technique was then carried out on the final mapped categories. Results: 916,619 individuals were included, with 93.1% meeting the authors' criteria for multimorbidity and 49.9% for polypharmacy. A seven-cluster solution was identified: one non-specific (Cluster 1) and six specific, corresponding to diabetes (Cluster 2), neurological and musculoskeletal, female dominant (Clusters 3 and 4) and cardiovascular, cerebrovascular and renal diseases (Clusters 5 and 6), and multi-system diseases (Cluster 7). Conclusions: This study utilized a mapping process combined with a soft clustering technique to determine combined patterns of multimorbidity and polypharmacy in the elderly population, identifying overrepresentation in six of the seven clusters with chronic disease and chronic disease-drug categories. These results could be applied to clinical practice guidelines in order to better attend to patient needs. This study can serve as the foundation for future longitudinal regarding relationships between multimorbidity and polypharmacy.
- Subjects :
- Gerontology
multimorbidity
Cross-sectional study
Health, Toxicology and Mutagenesis
Population
Primary health care
Diseases
elderly
Chronic disease
Clustering
Article
Persones grans
primary healthcare
Elderly
Combined patterns
Diabetes mellitus
Aprenentatge automàtic
Machine learning
medicine
Multimorbidity
Humans
Multiple Chronic Conditions
Medical prescription
polypharmacy
education
Aged
Polypharmacy
education.field_of_study
Primary Health Care
business.industry
Public Health, Environmental and Occupational Health
medicine.disease
Cross-Sectional Studies
Morbiditat
machine learning
combined patterns
Medicine
Female
Older people
business
Primary healthcare
chronic disease
clustering
Subjects
Details
- Language :
- English
- ISSN :
- 16617827 and 16604601
- Volume :
- 18
- Issue :
- 9216
- Database :
- OpenAIRE
- Journal :
- International Journal of Environmental Research and Public Health
- Accession number :
- edsair.doi.dedup.....4ef90f106f2e804d03a80bfeb1a54e63