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Ceftriaxone induced hemolysis complicated by acute renal failure
- Source :
- Pediatric Blood & Cancer. 50:139-142
- Publication Year :
- 2008
- Publisher :
- Wiley, 2008.
-
Abstract
- Over the last decade, second and third generation cephalosporins have been the most common drugs causing hemolytic anemia (HA). Of these cases, 20% have been attributed to ceftriaxone. The clinical presentation of ceftriaxone-induced HA is usually abrupt with sudden onset of pallor, tachypnea, cardio-respiratory arrest and shock. Acute renal failure (ARF) has been reported in 41% of such cases with a high fatality rate. We report a pediatric patient with ARF complicating ceftriaxone-induced HA who survived. Ceftriaxone is a commonly used drug, and early recognition of HA and institution of supportive care, including dialysis is likely to improve the outcome.
- Subjects :
- Male
Hemolytic anemia
Anemia, Hemolytic
Anemia
medicine.medical_treatment
Tachypnea
Pallor
Case fatality rate
medicine
Humans
Child
Dialysis
business.industry
Ceftriaxone
Hematology
Acute Kidney Injury
Kidney Tubular Necrosis, Acute
medicine.disease
Anti-Bacterial Agents
Oncology
Shock (circulatory)
Anesthesia
Pediatrics, Perinatology and Child Health
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 15455017 and 15455009
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- Pediatric Blood & Cancer
- Accession number :
- edsair.doi.dedup.....4f04293f79c73782eca706ff8d7e52a4