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Electroencephalographic Coherence in Alzheimer's Disease: Comparisons with a Control Group and Population Norms
- Source :
- Journal of Geriatric Psychiatry and Neurology. 13:1-8
- Publication Year :
- 2000
- Publisher :
- SAGE Publications, 2000.
-
Abstract
- Previous research from independent laboratories has shown reduced electroencephalographic coherence in patients diagnosed with dementia of the Alzheimer type (DAT). This study added to this work by comparing interhemispheric and intrahemispheric coherence in nonmedicated DAT patients (n = 35) with that of a normal control group (n = 30), as well as with a data bank of population norms. Raw and Z-score transformed values showed reduced coherence, interhemispherically (in delta, theta, alpha, and beta bands) and intrahemispherically (delta and theta bands) in DAT patients with both comparison procedures. Discriminant analysis correctly classified 73% to 75% of patients. The results are discussed in relation to earlier research, "trait" versus "state" factors, the cholinergic system, and cognitive processes in dementia. ( J Geriatr Psychiatry Neurol 2000; 13:1-8).
- Subjects :
- Male
medicine.medical_specialty
Population
Audiology
Electroencephalography
Developmental psychology
Central nervous system disease
03 medical and health sciences
0302 clinical medicine
Alzheimer Disease
medicine
Humans
Dementia
Dominance, Cerebral
education
Aged
Aged, 80 and over
Cerebral Cortex
education.field_of_study
medicine.diagnostic_test
Cognitive disorder
Cognition
Coherence (statistics)
medicine.disease
030227 psychiatry
Psychiatry and Mental health
Female
Neurology (clinical)
Geriatrics and Gerontology
Alzheimer's disease
Psychology
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15525708 and 08919887
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Journal of Geriatric Psychiatry and Neurology
- Accession number :
- edsair.doi.dedup.....4f315971e1685574fb75390d83e8f0ce