Ovarian reserve in young women of reproductive age with Crohn's disease

Background: Crohn's disease (CD) mainly affects young adults of reproductive age. Whereas a large amount of data is available concerning pregnancy in young CD women, no study has been conducted on their ovarian reserve status. This study aimed to investigate the potential effect of CD on ovarian reserve in young women in remission, as reflected by serum anti-Mullerian hormone (AMH). Methods: This retrospective case-control study was conducted in the University Hospital of Nantes, France. Serum levels of AMH were retrospectively measured in 50 women with CD in remission and in 163 control women with normal ovarian reserve, matched by age. Results: No statistical difference was found between mean serum AMH levels in CD and control women. Serum AMH levels remained comparable between CD and control women