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Etiology of Bacterial Meningitis Among Children <5 Years Old in Côte d’Ivoire: Findings of Hospital-based Surveillance Before and After Pneumococcal Conjugate Vaccine Introduction

Authors :
Flore Sandrine Zaba
Catherine Boni-cisse
Jason M. Mwenda
Bernard Ntsama
Alice Britoh-Mlan
Effua Usuf
Brenda Kwambana-Adams
Joseph Nsiari-Muzeyi Biey
Martin Antonio
Sheikh Jarju
Peter Sylvanus Ndow
N'zue Kofi
Nicaise Aka Lepri
Rowan E Bancroft
Archibald Worwui
Hamidou Kone
Source :
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Publication Year :
2019
Publisher :
Oxford University Press (OUP), 2019.

Abstract

Background Bacterial meningitis remains a major disease affecting children in C&#244;te d’Ivoire. Thus, with support from the World Health Organization (WHO), C&#244;te d’Ivoire has implemented pediatric bacterial meningitis (PBM) surveillance at 2 sentinel hospitals in Abidjan, targeting the main causes of PBM: Streptococcus pneumoniae (pneumococcus), Haemophilus influenzae, and Neisseria meningitidis (meningococcus). Herein we describe the epidemiological characteristics of PBM observed in C&#244;te d’Ivoire during 2010–2016. Methods Cerebrospinal fluid (CSF) was collected from children aged&lt;br /&gt;Longitudinal sentinel surveillance at 2 hospitals within Abidjan, C&#244;te d’Ivoire, during 2010–2016 revealed that Streptococcus pneumoniae was the predominant pathogen responsible for pediatric bacterial meningitis before and after the introduction of the 13-valent pneumococcal conjugate vaccine.

Details

ISSN :
15376591 and 10584838
Volume :
69
Database :
OpenAIRE
Journal :
Clinical Infectious Diseases
Accession number :
edsair.doi.dedup.....4fb9f5924d977f17a18a7f9e6564595b
Full Text :
https://doi.org/10.1093/cid/ciz475