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Tumor lysis syndrome in small cell lung cancer
- Source :
- Medical oncology (Northwood, London, England). 18(2)
- Publication Year :
- 2000
-
Abstract
- Tumor lysis syndrome, resulting from the abrupt release of intracellular ions into the blood stream due to sudden tumor cell death, is a serious complication of chemotherapy treatment. This syndrome occurs more frequently in hematologic malignancies and lymphomas. Its incidence in solid tumors is rare, but has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of tumor lysis syndrome accompanied by death in a patient with extensive stage small cell lung cancer who was treated with cisplatin and etoposide, and review the risk factors associated with the syndrome in solid tumor patients who are likely to respond to chemotherapy.
- Subjects :
- Oncology
Male
Cancer Research
medicine.medical_specialty
Lung Neoplasms
medicine.medical_treatment
Antineoplastic Agents
Biology
Fatal Outcome
Risk Factors
Internal medicine
medicine
Humans
Carcinoma, Small Cell
Etoposide
Cisplatin
Chemotherapy
Hematology
Mortality rate
General Medicine
Middle Aged
medicine.disease
Tumor lysis syndrome
Complication
Tumor Lysis Syndrome
Intracellular
medicine.drug
Subjects
Details
- ISSN :
- 13570560
- Volume :
- 18
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Medical oncology (Northwood, London, England)
- Accession number :
- edsair.doi.dedup.....4fd9be4b2b7565f79c565dcd0ec61e85