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The significance of clinical features in the prognosis of acute renal infarction: single center experience
- Source :
- Clinical and Experimental Nephrology. 16:611-616
- Publication Year :
- 2012
- Publisher :
- Springer Science and Business Media LLC, 2012.
-
Abstract
- Acute renal infarct (ARI) is a common renovascular disease caused by the abrupt interruption of renal blood flow. Since the presenting symptoms are often non-specific, a major concern in ARI has been prompt diagnosis, and its long-term outcome has never been studied. From January 2000 through to December 2009, adult patients with ARI were enrolled in this study. We retrospectively reviewed their clinical data, and followed them up until July 2011. Renal outcome and all-cause mortality were measured. A total of 67 patients were finally enrolled in this study. Their mean age was 56.1 ± 16.4 years, and 52.2% of them were male. Over 76% of patients were identified to have more than one comorbidity and concurrent thromboembolic events occurred in 16.4% of the patients. Although, acute kidney injury (AKI) was present in 40.7% of the patients, long-term renal outcome was relatively good. In all cases, AKI was resolved within a month, and renal loss was found in only one patient. In-hospital mortality was 8.9% and during the median follow-up period of 40.6 months, long-term mortality was 19.7%. Independent risk factors for mortality were age, atrial fibrillation, myocardial infarction and hematuria [hazard ratio (HR) 1.051, 95% confidence interval (CI) 1.008–1.096; HR 3.322, 95% CI 1.119–9.860; HR 9.315, 95% CI 1.555–55.796 and HR 7.745, 95% CI 1.606–37.353, respectively]. Our study suggested that in-hospital and long-term outcomes of ARI were closely related to the comorbidities or underlying disease of ARI, rather than the disease itself.
- Subjects :
- Adult
Male
Nephrology
medicine.medical_specialty
Physiology
Comorbidity
Kidney
Physiology (medical)
Internal medicine
medicine
Humans
Hospital Mortality
Myocardial infarction
Aged
Retrospective Studies
business.industry
Hazard ratio
Acute kidney injury
Retrospective cohort study
Acute Kidney Injury
Middle Aged
Prognosis
medicine.disease
Infarction
Renal blood flow
Female
business
Renal Infarct
Subjects
Details
- ISSN :
- 14377799 and 13421751
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Clinical and Experimental Nephrology
- Accession number :
- edsair.doi.dedup.....504ee2eb97ed2694e5df3a824dcac1bb