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Atrial fibrillation in chronic heart failure patients with reduced ejection fraction: The CHECK-HF registry
- Source :
- International Journal of Cardiology, 308, 60-66. Elsevier Ireland Ltd, International Journal of Cardiology, 308, 60-66. ELSEVIER IRELAND LTD
- Publication Year :
- 2020
-
Abstract
- Atrial fibrillation (AF) is common in chronic heart failure (HF) patients and influences the choice and effects of drug and device therapy. In this large real-world HF registry, we studied whether the presence of AF affects the prescription of guideline-recommended HF therapy.We analyzed 8253 patients with chronic HF with reduced ejection fraction (HFrEF) from 34 Dutch outpatient clinics included in the period between 2013 and 2016 treated according to the 2012 ESC guidelines.2109 (25.6%) of these patients were in AF (mean age 76.8 ± 9.2 years, 65.0% were men) and 6.144 (74.4%) had no AF (mean age 70.7 ± 12.2 years, 63.6% were men). Patients with AF more often received beta-blockers (81.7% vs. 79.7%, p = 0.04), MRAs (57.1% vs. 51.7%, p < 0.01), diuretics (89.7% vs. 80.6%, p < 0.01) and digoxin (40.1% vs. 9.3%, p < 0.01) compared to patients without AF, whereas they less often receive renin-angiotensin-system (RAS)-inhibitors (76.1% vs. 83.1%, p < 0.01). The number of patients who received beta-blockers, RAS-inhibitor and MRA at ≥50% of the recommended target dose was comparable between those with and without AF (16.6% vs. 15.2%, p = 0.07).In this large cohort of chronic HFrEF patients, the prevalence of AF was high and we observed significant differences in prescription of both guideline-recommended HF between patients with and without AF.Copyright © 2020 Elsevier B.V. All rights reserved.
- Subjects :
- Male
medicine.medical_specialty
Digoxin
Adrenergic beta-Antagonists
ESC
030204 cardiovascular system & hematology
GUIDELINES
03 medical and health sciences
0302 clinical medicine
Device therapy
Internal medicine
Atrial Fibrillation
medicine
MANAGEMENT
Outpatient clinic
Humans
030212 general & internal medicine
Registries
Aged
Aged, 80 and over
Heart Failure
left-ventricular dysfunction
Ejection fraction
sinus rhythm
business.industry
MORTALITY
BETA-BLOCKERS
Atrial fibrillation
Mean age
Stroke Volume
digoxin
Middle Aged
medicine.disease
collaboration
EUROPEAN-SOCIETY
Target dose
HOSPITALIZATION
Heart failure
2016 esc guidelines
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 01675273
- Database :
- OpenAIRE
- Journal :
- International Journal of Cardiology, 308, 60-66. Elsevier Ireland Ltd, International Journal of Cardiology, 308, 60-66. ELSEVIER IRELAND LTD
- Accession number :
- edsair.doi.dedup.....5069b4d444043a4cbad9dd7a8421f915