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Epicardial adipose tissue thickness is not associated with adverse cardiovascular events in patients undergoing haemodialysis
- Source :
- Scientific Reports, Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- In non-haemodialysis (HD) patients, increased epicardial adipose tissue (EAT) thickness was significantly associated with adverse cardiovascular (CV) events. This study was designed to investigate whether EAT thickness was a useful parameter in the prediction of adverse CV events in HD patients. In addition, we also evaluated the major correlates of EAT thickness in these patients. In 189 routine HD patients, we performed a comprehensive transthoracic echocardiographic examination with assessment of EAT thickness. The definition of CV events included CV death, non-fatal stroke, non-fatal myocardial infarction, peripheral artery disease, and hospitalization for heart failure. The follow-up period for CV events was 2.5 ± 0.7 years. Thirty-one CV events were documented. The multivariable analysis demonstrated that older age, smoking status, the presence of diabetes mellitus and coronary artery disease, and low albumin levels were independently correlated with adverse CV events. However, increased EAT thickness was not associated with adverse CV events (P = 0.631). Additionally, older age, female sex, low haemoglobin, and low early diastolic mitral annular velocity were correlated with high EAT thickness in the univariable analysis. In the multivariable analysis, older age and female sex were still correlated with high EAT thickness. In conclusion, high EAT thickness was associated with older age and female sex in the multivariable analysis in our HD patients. However, EAT thickness was not helpful in predicting adverse CV events in such patients. Further large-scale studies are necessary to verify this finding.
- Subjects :
- Male
medicine.medical_specialty
Cardiology
lcsh:Medicine
030209 endocrinology & metabolism
Disease
030204 cardiovascular system & hematology
Article
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Renal Dialysis
Risk Factors
Diabetes mellitus
Internal medicine
medicine
Humans
In patient
Myocardial infarction
lcsh:Science
Stroke
Aged
Multidisciplinary
business.industry
lcsh:R
Middle Aged
medicine.disease
Adipose Tissue
Nephrology
Cardiovascular Diseases
Heart failure
Epicardial adipose tissue
lcsh:Q
Female
business
Pericardium
Subjects
Details
- ISSN :
- 20452322
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....507014a026f3fe85a7a335e7ae50bb19