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Immuno-Electron Microscopic Study of Keratin Distribution in the Cochlea Using Monoclonal Antibody
- Source :
- Annals of Otology, Rhinology & Laryngology. 99:817-826
- Publication Year :
- 1990
- Publisher :
- SAGE Publications, 1990.
-
Abstract
- Keratin distribution in the cochlea has been studied immuno–electron microscopically by both pre-embedding and postembedding methods. Keratin immunoreactivity in the guinea pig cochlea was clearly demonstrated in Hensen's cells, the reticular lamina surrounding both outer and inner hair cells, outer and inner pillar cells, Claudius' cells, inner and external sulcus cells, interdental cells of the spiral limbus, Reissner's membrane, border cells, inner phalangeal cells, Deiters' cells, and spiral prominence cells. Keratin expression at the ultrastructural level showed a nonfilamentous keratin system in the cytoplasm of cochlear supporting cells.
- Subjects :
- 0301 basic medicine
Pathology
medicine.medical_specialty
Spiral limbus
Guinea Pigs
Biology
03 medical and health sciences
0302 clinical medicine
Keratin
Border cells
otorhinolaryngologic diseases
medicine
Animals
Inner ear
Microscopy, Immunoelectron
030223 otorhinolaryngology
Cochlea
chemistry.chemical_classification
integumentary system
030102 biochemistry & molecular biology
Antibodies, Monoclonal
General Medicine
Immunohistochemistry
Cell biology
medicine.anatomical_structure
Otorhinolaryngology
chemistry
Cytoplasm
Reticular connective tissue
Ultrastructure
Keratins
sense organs
Subjects
Details
- ISSN :
- 1943572X and 00034894
- Volume :
- 99
- Database :
- OpenAIRE
- Journal :
- Annals of Otology, Rhinology & Laryngology
- Accession number :
- edsair.doi.dedup.....50a38d620bf1022af888c29ce35b62a0