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Intermittent fasting: from calories to time restriction
- Source :
- GeroScience. 43(3)
- Publication Year :
- 2021
-
Abstract
- The global human population has recently experienced an increase in life expectancy with a mounting concern about the steady rise in the incidence of age-associated chronic diseases and socio-economic burden. Calorie restriction (CR), the reduction of energy intake without malnutrition, is a dietary manipulation that can increase health and longevity in most model organisms. However, the practice of CR in day-to-day life is a challenging long-term goal for human intervention. Recently, daily fasting length and periodicity have emerged as potential drivers behind CR's beneficial health effects. Numerous strategies and eating patterns have been successfully developed to recapitulate many of CR's benefits without its austerity. These novel feeding protocols range from shortened meal timing designed to interact with our circadian system (e.g., daily time-restricted feeding) to more extended fasting regimens known as intermittent fasting. Here, we provide a glimpse of the current status of knowledge on different strategies to reap the benefits of CR on metabolic health in murine models and in humans, without the rigor of continuous reduction in caloric intake as presented at the USU State of the Science Symposium.
- Subjects :
- Aging
Calorie
media_common.quotation_subject
Calorie restriction
Population
Mice
Environmental health
Intermittent fasting
medicine
Animals
Humans
education
media_common
Caloric Restriction
Meal
education.field_of_study
business.industry
Longevity
Fasting
Feeding Behavior
medicine.disease
Diet
Malnutrition
Life expectancy
Geriatrics and Gerontology
business
Energy Intake
Subjects
Details
- ISSN :
- 25092723
- Volume :
- 43
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- GeroScience
- Accession number :
- edsair.doi.dedup.....50b5c6e81e1897ef4774a874b36b1624