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Liuweidihuang-tang improves spatial memory function and increases neurogenesis in the dentate gyrus in rats
- Source :
- Fitoterapia. 76:514-519
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- The aqueous extract of Liuweidihuang-tang given to rats at doses of 100 mg/kg/day for 10 days induced a reduction in the frequency of error and increased neurogenesis in the hippocampal dentate gyrus. Our data suggest that Liuweidihuang-tang improves spatial learning ability by increasing neurogenesis in the dentate gyrus.
- Subjects :
- Male
medicine.medical_specialty
Biology
Hippocampal formation
Rats, Sprague-Dawley
Memory
Internal medicine
Drug Discovery
medicine
Animals
Neurons
Pharmacology
Aqueous extract
Plants, Medicinal
Radial arm maze
Dose-Response Relationship, Drug
Dentate gyrus
Neurogenesis
General Medicine
Immunohistochemistry
Rats
Sprague dawley
Endocrinology
Space Perception
Dentate Gyrus
Exploratory Behavior
Spatial learning
Drugs, Chinese Herbal
Phytotherapy
Subjects
Details
- ISSN :
- 0367326X
- Volume :
- 76
- Database :
- OpenAIRE
- Journal :
- Fitoterapia
- Accession number :
- edsair.doi.dedup.....50c8f9b905aa0fefed66d373eecb7a0d