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Liuweidihuang-tang improves spatial memory function and increases neurogenesis in the dentate gyrus in rats

Authors :
Geon Ho Bahn
Baek-Vin Lim
Jae Hyung Park
Chang-Ju Kim
Kwang Sik Lee
Hyun-Kyung Chang
Eun-Kyung Paik
Hye-Young Yang
Source :
Fitoterapia. 76:514-519
Publication Year :
2005
Publisher :
Elsevier BV, 2005.

Abstract

The aqueous extract of Liuweidihuang-tang given to rats at doses of 100 mg/kg/day for 10 days induced a reduction in the frequency of error and increased neurogenesis in the hippocampal dentate gyrus. Our data suggest that Liuweidihuang-tang improves spatial learning ability by increasing neurogenesis in the dentate gyrus.

Details

ISSN :
0367326X
Volume :
76
Database :
OpenAIRE
Journal :
Fitoterapia
Accession number :
edsair.doi.dedup.....50c8f9b905aa0fefed66d373eecb7a0d