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Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023

Authors :
Charlotte Nielsen Agergaard
Lone Jannok Porsbo
Thomas Vognbjerg Sydenham
Sanne Grønvall Kjær Hansen
Kat Steinke
Sanne Løkkegaard Larsen
Kristján Orri Helgason
Frank Hansen
Kasper Thystrup Karstensen
Anna E Henius
Barbara Juliane Holzknecht
Lillian Søes
Kristian Schønning
Mikala Wang
Nina Ank
Anna Margrét Halldórsdóttir
Ólafur Guðlaugsson
Anette M Hammerum
Anne Kjerulf
Brian Kristensen
Henrik Hasman
Ulrik Stenz Justesen
Source :
Agergaard, C N, Porsbo, L J, Sydenham, T V, Hansen, S G K, Steinke, K, Larsen, S L, Helgason, K O, Hansen, F, Karstensen, K T, Henius, A E, Holzknecht, B J, Søes, L, Schønning, K, Wang, M, Ank, N, Halldórsdóttir, A M, Guðlaugsson, Ó, Hammerum, A M, Kjerulf, A, Kristensen, B, Hasman, H & Justesen, U S 2023, ' Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 ', Eurosurveillance, vol. 28, no. 9 . https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108, Agergaard, C N, Porsbo, L J, Sydenham, T V, Hansen, S G K, Steinke, K, Larsen, S L, Helgason, K O, Hansen, F, Karstensen, K T, Henius, A E, Holzknecht, B J, Søes, L, Schønning, K, Wang, M, Ank, N, Halldórsdóttir, A M, Guðlaugsson, Ó, Hammerum, A M, Kjerulf, A, Kristensen, B, Hasman, H & Justesen, U S 2023, ' Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 ', Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, vol. 28, no. 9 . https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108
Publication Year :
2023

Abstract

From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. An NDM-5/OXA-48-carbapenemase-producing E. hormaechei ST79, identical to patient isolates, was cultured from the surface of dicloxacillin capsules in Denmark, strongly implicating them as the source of the outbreak. Special attention is required to detect the outbreak strain in the microbiology laboratory. From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. An NDM-5/OXA-48-carbapenemase-producing E. hormaechei ST79, identical to patient isolates, was cultured from the surface of dicloxacillin capsules in Denmark, strongly implicating them as the source of the outbreak. Special attention is required to detect the outbreak strain in the microbiology laboratory.

Details

Language :
English
Database :
OpenAIRE
Journal :
Agergaard, C N, Porsbo, L J, Sydenham, T V, Hansen, S G K, Steinke, K, Larsen, S L, Helgason, K O, Hansen, F, Karstensen, K T, Henius, A E, Holzknecht, B J, Søes, L, Schønning, K, Wang, M, Ank, N, Halldórsdóttir, A M, Guðlaugsson, Ó, Hammerum, A M, Kjerulf, A, Kristensen, B, Hasman, H & Justesen, U S 2023, ' Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 ', Eurosurveillance, vol. 28, no. 9 . https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108, Agergaard, C N, Porsbo, L J, Sydenham, T V, Hansen, S G K, Steinke, K, Larsen, S L, Helgason, K O, Hansen, F, Karstensen, K T, Henius, A E, Holzknecht, B J, Søes, L, Schønning, K, Wang, M, Ank, N, Halldórsdóttir, A M, Guðlaugsson, Ó, Hammerum, A M, Kjerulf, A, Kristensen, B, Hasman, H & Justesen, U S 2023, ' Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 ', Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, vol. 28, no. 9 . https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108
Accession number :
edsair.doi.dedup.....5150eca4dc139fd736e846be5156baa1
Full Text :
https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108