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Low risk of renal flares and negative outcomes in women with lupus nephritis conceiving after switching from mycophenolate mofetil to azathioprine

Authors :
Matthias Schneider
Rebecca Fischer-Betz
Martin Aringer
Christof Specker
Ralph Brinks
Source :
Rheumatology. 52:1070-1076
Publication Year :
2013
Publisher :
Oxford University Press (OUP), 2013.

Abstract

Objective. MMF is teratogenic and needs to be replaced before pregnancy. This change may lead to flares. Our aim was to determine the risk of renal flares in women with LN who switched treatment from MMF to AZA before conception and to evaluate the outcome of their pregnancies. Methods. Medical records of women with LN counselled for pregnancy wish were reviewed. Women receiving treatment with either MMF or AZA (control group), with inactive lupus (SLEDAI4 4) and quiescent LN (serum creatinine

Details

ISSN :
14620332 and 14620324
Volume :
52
Database :
OpenAIRE
Journal :
Rheumatology
Accession number :
edsair.doi.dedup.....51a3f98dadf553a37c18558e37da0858
Full Text :
https://doi.org/10.1093/rheumatology/kes425