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Furanosic forms of sugars: conformational equilibrium of methyl β-<scp>d</scp>-ribofuranoside

Authors :
Patricia Écija
Lorenzo Spada
Emilio J. Cocinero
Francisco J. Basterretxea
Iciar Uriarte
Alberto Lesarri
Walther Caminati
Benjamin G. Davis
Écija, Patricia
Uriarte, Iciar
Spada, Lorenzo
Davis, Benjamin G.
Caminati, Walther
Basterretxea, Francisco J.
Lesarri, Alberto
Cocinero, Emilio J.
Source :
UVaDOC. Repositorio Documental de la Universidad de Valladolid, instname
Publication Year :
2016
Publisher :
Royal Society of Chemistry (RSC), 2016.

Abstract

The investigation of an isolated ribofuranose unit in the gas phase reveals the intrinsic conformational landscape of the biologically active sugar form.We report the rotational spectra of two conformers of methyl b-D-ribofuranoside in a supersonic jet expansion. Both conformers adopt a near twisted (3T2) ring conformation with the methoxy and hydroxymethyl substituents involved in various intramolecular hydrogen bonds.&lt;br /&gt;MINECO-FEDER CTQ2015-68148-C2-P

Details

ISSN :
1364548X and 13597345
Volume :
52
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi.dedup.....51be40950704d0a0cae5b0f72f9099dd